Pulsetto Rehab Pilot Program

1. 30 / 60 / 90-day cohorts

2. Clinical onboarding & training

3. App + clinician dashboard access

4. Pre/Post outcome reporting

Eligibility:
Rehab centers | Veteran programs | Military medical units | NGOs

Measure:
HRV, recovery indices, psychometric scales, sleep logs

Clinical & Field Evidence

Results from the Lithuanian Riflemen’s Union:

In a separate group, short 10–15 minute Pulsetto sessions showed promising effects:

• Participants felt less fatigue and more refreshed compared to the control group who only rested.

• During evening sessions, the sleep program reduced heart rate by an average of 15% in about 10 minutes, indicating strong physiological calming.

• Most participants reported feeling less tense and in a stable or positive mood, which is ideal before sleep.

Results from Grey Team Veterans (USA):

We conducted a post-survey with 7 veterans, and the feedback was very encouraging:

• 57% reported reduced stress and anxiety, better sleep, and a noticeable sense of physical relaxation.

• Most users experienced benefits within just 1–2 weeks.

• 57% said they see Pulsetto as either an alternative or a complement to medication or therapy.

Non-invasive Vagus Nerve Stimulation in Post-Traumatic Stress Disorder

A comprehensive review and clinical practice guideline concluded that non-invasive vagus nerve stimulation (nVNS) is safe and can significantly reduce PTSD symptoms. In studies involving diagnosed patients as well as trauma-exposed individuals without a formal diagnosis, nVNS demonstrated:

• Reduction of PTSD symptoms after 3 months of use (p < 0.05)

• Improved autonomic balance — decreased sympathetic activity and increased parasympathetic activity

• Better attention control and memory

• Reduced reactivity to emotional stressors

• Focus: Clinical efficacy and mechanisms of cervical nVNS for PTSD.

Transcutaneous cervical vagus nerve stimulation enhances second-language vocabulary acquisition while simultaneously mitigating fatigue and promoting focus

A study conducted at the U.S. Defense Language Institute showed that nVNS stimulation improved learning speed and retention, reduced perceived fatigue, and enhanced attention. The participants were professional military linguists, and the effect was observed even within this highly trained and high-performance group. This confirms that nVNS is effective even among highly motivated and well-conditioned soldiers.

Focus: Learning performance, attention, and fatigue in cognitively demanding military language training.

Assessed variables:
1) Declarative memory (number of learned vocabulary words)

2) Subjective fatigue (0–100 scale)

3) Perceived focus and alertnessLearning efficiency (retention across sessions)

4) Comparison between ctVNS and sham stimulation

Preliminary evidence of transcutaneous vagus nerve stimulation effects on sleep in veterans with post-traumatic stress disorder

A study involving 13 U.S. military veterans with a confirmed PTSD diagnosis found that one hour of transcutaneous vagus nerve stimulation (tVNS) before bedtime may positively affect sleep quality and autonomic nervous system activity. Although total sleep time slightly decreased, researchers observed an increase in the duration of deep (N3) sleep, a reduction in the cyclic alternating pattern (CAP) index, and elevated parasympathetic activity (RSAP-B) during NREM sleep. These physiological changes indicate improved sleep quality and stability, despite some participants subjectively rating their sleep as worse.The authors concluded that tVNS may be a promising strategy to improve sleep and reduce PTSD symptoms, particularly when symptoms are linked to sleep disturbances.
Focus: Sleep quality and autonomic function in PTSD-diagnosed veterans.
Assessed variables:

• Sleep architecture (via polysomnography), including N3 deep sleep phase

• CAP index (cyclic alternating pattern)

• Parasympathetic activity during NREM sleep (RSAP-B)

• Total sleep time (TST)

• Subjective sleep quality before and after tVNS session

From Stress to Strength: Voices of Change

My name is William Moschetti.

I'm a 26-year retired veteran from the United States Army, formerly a Green Beret. And I was introduced to this Pulsetto device when I came to the Grey team. And I've used this extensively throughout the whole program, and it's really helped me with anxiety, and most of all, sleep. I've used it by waking up in the middle of the night and using it for six minutes for the sleep setting, and it's helped calm my mind down. And also on the app, the breathing exercises have really played a significant role in helping me sleep in conjunction with using the device.

They've allowed me to be able to keep mine, so I'll continue to use it until it wears out, and I'll get another one.

Security & Data Integrity

Pulsetto nVNS is a wellness-classified device.

Not yet cleared for therapeutic PTSD/TBI treatment.

Clinical pilots under ethical standards & informed consent.

Have questions? We are hereto answer.

Jūratė Kiršė
CEO of Pulsetto Medical
Head of Clinical Research and Regulatory Strategy

jurate@pulsetto.tech
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